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Table 2 Evidence for left atrial strain in patients with HFpEF

From: Left ventricular and atrial myocardial strain in heart failure with preserved ejection fraction: the evidence so far and prospects for phenotyping strategy

Invasive Hemodynamic outcomes

Published trials

LVEDP

Cameli et al., 2016 [45]

Lin et al., 2020 [46]

Ma et al., 2022 [47]

Zhou et al., 2021 [48]

PAWP

Reddy et al., 2019 [49]

Lundberg et al., 2019 [50]

Telles et al., 2019 [51]

LV pre-A pressure

Singh et al., 2019 [52]

LV pre-A pressure/PAWP

Inoue et al., 2021 [53]

LVEDP/PAWP

Hummel et al., 2017 [54]

LVEDP/LV pre-A pressure

Nishida et al., 2023 [41]

Clinical outcomes

 All-cause/cardiovascular mortality or HF hospitalization

Park et al., 2020 [55]

Bouwmeester et al., 2022 [56]

Ersbøll et al., 2013 [57]

Kim et al., 2020 [58]

Inciardi et al., 2022 [59]

Shin et al., 2021 [60]

Oike et al., 2021 [61]

 Atrial fibrillation

Jasic-Szpak et al., 2021 [62]

Weber et al., 2021 [63]

  1. Adapted from Nagueh et al. [64]. Legend: LVEPD Left Ventricular End Diastolic Pressure, PAWP Pulmonary Arterial Wedge Pressure, LV Left Ventricular, pre-A pre-atrial contraction, HF Heart Failure