Left ventricular and atrial myocardial strain in heart failure with preserved ejection fraction: the evidence so far and prospects for phenotyping strategy

Table 1 Some studies analyzing the GLS thresholds in patients with HFpEF

Trial	Strain Analysis (N)	GLS normal	GLS abnormal	Cut off for abnormal GLS
TOPCAT [33]	447	48%	52%	-15.8%
RELAX [34]	187	35%	65%	-16%
Donal et al. [35]	237	33%	67%	-16%
Buggey et al. [36]	739	24%	76%	-16%
PARAMOUNT HF [37]	219	33%	67%	-15.8%
Huang et al. [38]	129	24.1%	75.9%	-15.8%
Morris et al. [39]	119	18.5%	81.5%	-16%

Adapted from: Argulian E, et al. [32]. GLS Left Ventricular Global Longitudinal Strain

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