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Table 7 TGLS in healthy controls and patients with or without drug adjustment

From: Layer‐specific strain echocardiography may reflect regional myocardial impairment in patients with hypertrophic cardiomyopathy

 

Healthy controls (n = 30)

Patients without drug adjustment (n = 22)

Patients received drug adjustment (n = 28)

 

Baseline echo

Follow-up echo

Baseline echo

Follow-up echo

Baseline echo

Follow-up echo

LVEF, %

64.3 ± 6.4

65.6 ± 5.7

70.8 ± 6.1

69.6 ± 7.3

72.7 ± 5.4

73.7 ± 6.5

Resting LVOT gradient, mmHg

7.8 ± 1.6

7.0 ± 2.1

18.2 (6.1—30.3)

18.0 (6.0—30.0)

70.0 (47.0—90.0)

40.0 (17.0—68.0) *

Global LS, %

-20.3 ± 6.84

-22.6 ± 5.49

-12.3 ± 7.87

-12.3 ± 8.79

-13.7 ± 10.10

-14.7 ± 9.70

TGLS basal, %

−2.17 ± 1.66

−2.58 ± 1.03

-1.22 ± 2.10

-1.19 ± 2.70

-1.01 ± 2.14

-1.71 ± 2.98**

TGLS mid, %

−3.58 ± 2.29

−3.27 ± 2.88

-3.28 ± 2.48

-2.98 ± 2.39

-2.72 ± 2.50

-3.31 ± 2.64**

TGLS apex, %

−10.54 ± 3.20

−11.10 ± 4.21

-9.9 ± 3.99

-9.5 ± 3.75

-9.8 ± 4.11

-10.21 ± 3.79

Number of segments with abnormal TGLS

6

8

72

79

145

84***

  1. LVEF left ventricular ejection fraction; LVOT left ventricular outflow tract; LS longitudinal strain; TGLS transmural gradient of longitudinal strain. *, **, ***: p < 0.05, 0.01, 0.001, compared with baseline data in patients received drug adjustment