Diastolic function and its association with diabetes, hypertension and age in an outpatient population with normal stress echocardiography findings

Table 5 Multiple linear regression models

Dependent	Diabetes		Hypertension		Sex (male)		Age (per year)
Dependent	B	p	B	p	B	p	B	p	R²	p*
LAVI, ml/m²	− 0.7	0.16	1.4	0.007	− 0.9	0.04	0.10	< 0.001	0.10	< 0.001
Septal e’, cm/s	−0.8	< 0.001	− 0.7	< 0.001	− 0.2	0.09	− 0.09	< 0.001	0.48	< 0.001
Lateral e’, cm/s	−0.8	< 0.001	− 0.8	< 0.001	0.2	0.21	−0.10	< 0.001	0.44	< 0.001
E/A, ratio	−0.10	0.002	−0.10	0.004	−0.03	0.34	−0.02	< 0.001	0.34	< 0.001
Mean E/e’, ratio	0.8	< 0.001	0.9	< 0.001	− 0.9	< 0.001	0.07	< 0.001	0.31	< 0.001
c¸ g/s	0.01	0.98	0.7	0.10	−1.3	0.001	0.07	< 0.001	0.10	< 0.001
k, g/s²	−12	0.01	−0.4	0.94	−20	< 0.001	− 0.20	0.29	0.05	< 0.001
x₀, cm	0.4	0.10	0.4	0.12	−0.4	0.07	0.01	0.22	0.03	0.001
c²-4k, g²/s²	52	0.009	30	0.16	33	0.07	3.6	< 0.001	0.11	< 0.001
Tau, ms	2.0	0.19	3.0	0.06	0.3	0.82	0.39	< 0.001	0.17	< 0.001
KFEI, %	−0.4	0.18	−0.7	0.04	0.4	0.18	− 0.068	< 0.001	0.14	< 0.001
Energy, mJ	0.01	0.85	0.09	0.14	−0.22	< 0.001	0.0005	0.83	0.04	< 0.001
Peak driving force, mN	−0.6	0.36	0.7	0.29	−3.1	< 0.001	−0.01	0.59	0.06	< 0.001
Peak resistive force, mN	−0.2	0.66	0.6	0.17	−2.1	< 0.001	0.02	0.29	0.07	< 0.001

LAVI Left atrial volume index. c Viscoelastic energy loss, k Stiffness, x₀ Load, KFEI Kinematic filling efficiency index. R² is adjusted R². *These p-values are for the overall model using the F-test

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