Table 1 Clinical characteristics, serum levels of cardiac biomarkers, and the main echocardiographic parameters of the 55 CA patients, grouped according to the presence or absence of aortic valve stenosis
Patients without AS (n = 50) | Patients with AS (n = 5) | p-value | |
|---|---|---|---|
Clinical data | |||
Age (years) | 63.5 (58–73) | 69 (68–82) | p = 0.055 |
Male (n, %) | 26 (52%) | 3 (60%) | p = 0.553 |
wtTTR CA (n, %) | 2 (4%) | 1 (20%) | p = 0.391 |
mTTR CA (n, %) | 6 (12%) | 0 (0%) | p = 0.485 |
AL amyloidosis (n, %) | 40 (80%) | 4 (80%) | p = 0.741 |
AA amyloidosis (n, %) | 1 (2%) | 0 (0%) | p = 0.909 |
NYHA III-IV stage (n, %) | 32 (64%) | 5 (100%) | p = 0.278 |
Atrial fibrillation (n, %) | 11 (22%) | 1 (20%) | p = 0.312 |
Laboratory data | |||
B-type natriuretic peptide (pg/ml) | 606 (234–1240) | 341 (77–657) | p = 0.303 |
Troponin T (ng/L) | 66 (39–104) | 134 (47–215) | p = 0.464 |
Echocardiography | |||
Left ventricular ejection fraction (%) | 56 (43–63) | 59 (51–60) | p = 0.823 |
Septal wall thickness (mm) | 16 (13–18) | 17 (13–20) | p = 0.578 |
Inferior wall thickness (mm) | 15 (13–17) | 15 (13–16) | p = 0.780 |
Left ventricular end diastolic diameter (mm) | 42 (36–45) | 41 (37–42) | p = 0.776 |
E/e’ (Average of lateral and septal e’) | 20.6 (16–24) | 18.1 (16.9–20.6) | p = 0.241 |
Lateral S′ | 5.5 (4–7) | 6.25 (4,25–8.3) | p = 0.588 |