Table 1 Baseline characteristics
From: Index of contractile asymmetry improves patient selection for CRT: a proof-of-concept study
All subjects (n = 89) | Responders (n = 66) | Non-responders (n = 23) | p-value | |
|---|---|---|---|---|
Age, yrs | 68 ± 9 | 67 ± 10 | 71 ± 8 | 0.05 |
Female, n (%) | 33 (37.1) | 27 (40.9) | 6 (26.1) | 0.32 |
Ischemic etiology, n (%) | 54 (61) | 38 (57.6) | 16 (69.6) | 0.34 |
NYHA-class | 1 | |||
I, n (%) | 1 (1.1) | 1 (1.5) | 0 (0) | |
II, n (%) | 30 (33.7) | 23 (34.8) | 7 (30.4) | |
III, n (%) | 58 (65.2) | 43 (65.2) | 15 (65.2) | |
ACEI/ARB, n (%) | 87 (97.8) | 64 (97) | 23 (100) | 0.99 |
Beta-blockers, n (%) | 85 (95.5) | 63 (95.5) | 22 (95.7) | 0.99 |
Loop diuretics, n (%) | 58 (65.2) | 40 (60.6) | 18 (78.3) | 0.2 |
Aldosterone antagonists, n (%) | 49 (55.1) | 35 (53) | 14 (60.9) | 0.63 |
Statins, n (%) | 63 (70.8) | 45 (68.2) | 18 (78.3) | 0.43 |
eGFR < 60 ml/min/1.73 m2, n (%) | 38 (42.7) | 24 (36.4) | 14 (60.9) | 0.05 |
LVESV, ml | 132.4 ± 52.9 | 131.9 ± 56.6 | 133.9 ± 41.3 | 0.86 |
LVEF, % | 27.1 ± 7.1 | 27.3 ± 6.9 | 26.6 ± 7.7 | 0.7 |
GLS, % | −9.5 ± 3.4 | −9.7 ± 3.7 | −8.7 ± 2.5 | 0.12 |
Mechanical dispersion, ms | 97 ± 32 | 97 ± 32 | 96 ± 34 | 0.95 |
QRS duration, ms | 163 ± 20 | 163 ± 18 | 162 ± 26 | 0.83 |