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Table 4 Effect of PMVR on mitral regurgitation, 6-min walk and LV remodelling

From: 3D vena contracta area after MitraClip© procedure: precise quantification of residual mitral regurgitation and identification of prognostic information

 

Before PMVR

After PMVR

p-value

MR grade median (P25;P75)

4 (3.5;4.0)

1 (0.5;1.5)

< 0.001

6 min walk [m]

257.5 ± 82.5

295.7 ± 96.3

< 0.01

VCA (3D) [cm2] median (P25;P75)

0.89 (0.65;1.33)

0.17 (0.09;0.37)

< 0.0001

NT-proBNP [pg/ml] median(P25;75)

3618 (1619;5782)

3247 (2273;4693)

0.954

LV end-diastolic volume [ml/m2]

85.0 ± 26.5

79.4 ± 23.2

0.17

LV end-systolic volume [ml/m2]

49.8 ± 22.2

44.7 ± 17.4

0.11

LV ejection fraction [%]

42.5 ± 12.5

43.6 ± 10.1

0.51

  1. PMVR decreased mitral regurgitation and improved six-minute walking distance in a follow-up examination 4 weeks after the intervention. NT-proBNP and left-ventricular volumes and ejection fraction remained unchanged. Shown are mean ± standard deviation, if not indicated otherwise
  2. PMVR percutaneous mitral valve repair, LV left ventricular, MR mitral regurgitation, VCA (3D) vena contracta area determined by direct planimetry in a 3D–coulor Doppler full volume