Left ventricular outflow tract velocity time integral outperforms ejection fraction and Doppler-derived cardiac output for predicting outcomes in a select advanced heart failure cohort

Table 2 Comparison of baseline variables by outcome group: Primary outcome vs Event free subgroups

Variable	Primary outcome group (n = 30)	Event-free group (n = 70)	p-value
LVOT VTI	8.0	8.5	0.039
Ejection fraction (%)	32.3	27.4	0.169
Doppler derived cardiac output (L/min)	2.29	2.44	0.217
Age, years	80.1 ± 11.3	70.7 ± 15.1	0.003
NYHA class (% in stage III or IV)	80%	48.60%	0.014
Hemoglobin, g/dL	12.7 ± 1.4	13.5 ± 2.2	0.030
Blood urea nitrogen, g/dL	33.8 ± 15.4	24.1 ± 12.5	0.001
GFR <60 ml/min	75.90%	53.10%	0.038
Pulmonary artery pressure, mmHg	53.0 ± 16.9	45.3 ± 12.6	0.019

Primary outcome was met in 30 subjects (28 death and 2 LVADs); Event free subjects were those alive at one year of follow up from TTE and without requirement for mechanical circulatory support
Abbrev: GFR glomerular filtration rate, LVOT VTI Left ventricular outflow tract velocity time integral, NYHA New York Heart Association

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