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Table 2 Laboratory parameters

From: Anti-inflammatory and morphologic effects of pitavastatin on carotid arteries and thoracic aorta evaluated by integrated backscatter trans-esophageal ultrasound and PET/CT: a prospective randomized comparative study with pravastatin (EPICENTRE study)

 

Pitavastatin

Pravastatin

 

Baseline

After 6 months

Baseline

After 6 months

Total cholesterol, mg/dl

202 ± 67

154 ± 22*

225 ± 21

185 ± 16*

LDL cholesterol, mg/dl

150 ± 21

80 ± 16*†

142 ± 24

103 ± 18*

HDL cholesterol, mg/dl

52 ± 12

52 ± 11

54 ± 15

55 ± 13

Triglyceride, mg/dl

134 ± 35

107 ± 52

167 ± 63

135 ± 71

AST, IU/l

28 ± 13

26 ± 5

34 ± 18

32 ± 13

ALT, IU/l

27 ± 17

25 ± 9

29 ± 15

30 ± 12

γ-GTP, IU/l

34 ± 19

38 ± 28

79 ± 89

76 ± 84

CK, IU/l

77 ± 31

85 ± 26

95 ± 53

108 ± 63

High-sensitive CRP, μg/l

2,883 ± 4,176

3,581 ± 8,445

1,747 ± 2,239

3,928 ± 5,025

Hemoglobin A1c, %

5.8 ± 0.8

5.9 ± 0.7

5.4 ± 0.5

5.5 ± 0.4

Insulin, μU/ml

7.0 ± 4.7

6.7 ± 3.5

5.4 ± 2.9

4.7 ± 2.6

  1. LDL: low density lipoprotein, HDL: high density lipoprotein, AST: aspartate aminotransferase, ALT: alanine aminotransferase, CRP: C-reactive protein, CK: creatinine phosphokinase, *p < 0.05 vs baseline, p < 0.05 vs pravastatin.